Upcoming Event: CSEM Student Forum

Proteolysis-Targeting Chimeras: Mechanism of Action and Computational Design

Stan Li, CSEM Student, Oden Institute

Abstract

PROteolysis-TArgeting Chimeras (PROTACs) are an emerging class of non-traditional small-molecule drugs and have become a hot topic in pharmacology. In this talk, I am hoping to share my understanding of what PROTACs are, how they work, why they became popular, and will cover some numerical/computational methods for PROTAC design, including our lab's work.

Biography

Stan completed his B.S. in Biochemistry at SUNY Stony Brook, and after that joined the Kozakov Group -- learning about applying math, physics, and statistics to solve biological questions. That inspired him to start his PhD program in Computational Biology to tackle problems in biology while integrating his wet-lab skills into his research.